Maak kennis met Rossella

It has already been shown that air pollution particles can reach the placenta, even at the fetal side. But what are the possible health effects? In this study I aim to unravel which molecular mechanisms related to cellular senescence (a form of cellular aging) are triggerd in the placenta by air pollution exposure during pregnancy. Understanding these molecular mechanisms is important since stress-induced premature senescence (SIPS) in the placenta has already been linked to pathologies such as preeclampsia, intrauterine growth restriction, spontaneous preterm birth and fetal death.