Limburgs Geboortecohort

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Gespecialiseerd in placenta gezondheid

Joline Millen

PhD student

Onderzoeksproject: The impact of ambient air pollution during gestation on placental senescence
Laatste studies: Master Biomedical sciences: Environmental Health Sciences – Hasselt University

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Onderzoeksproject

The impact of ambient air pollution during gestation on placental senescence

It has already been shown that air pollution particles can reach the placenta, even at the fetal side. But what are the possible health effects? In this study I aim to unravel which molecular mechanisms related to cellular senescence (a form of cellular aging) are triggerd in the placenta by air pollution exposure during pregnancy. Understanding these molecular mechanisms is important since stress-induced premature senescence (SIPS) in the placenta has already been linked to pathologies such as preeclampsia, intrauterine growth restriction, spontaneous preterm birth and fetal death.